A truly unique find: card number 1 of 1. The Upper Deck 2008 SP Legendary Cuts "Hair Cut Signatures" card. The card features a small piece of Abraham Lincoln's hair as well as a cutting of his signature. Lincoln usually signed documents with his famous "A. Lincoln" autograph, but this one is the longer version, "Abraham Lincoln."
The card is listed for $21,400, but the seller (beckettmedia) is considering best offers.
[May 9, 2009 update: This card sold for $17,500. The best part: My friend bought it! I'll get to see it soon.]
see the original eBay listing
Like me, you may never get to splurge on something like this, but click through to the eBay listing to check it out for yourself. It's total eye candy!